Ontology highlight
ABSTRACT:
SUBMITTER: Madore C
PROVIDER: S-EPMC7704669 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Madore C C Leyrolle Q Q Morel L L Rossitto M M Greenhalgh A D AD Delpech J C JC Martinat M M Bosch-Bouju C C Bourel J J Rani B B Lacabanne C C Thomazeau A A Hopperton K E KE Beccari S S Sere A A Aubert A A De Smedt-Peyrusse V V Lecours C C Bisht K K Fourgeaud L L Gregoire S S Bretillon L L Acar N N Grant N J NJ Badaut J J Gressens P P Sierra A A Butovsky O O Tremblay M E ME Bazinet R P RP Joffre C C Nadjar A A Layé S S
Nature communications 20201130 1
Omega-3 fatty acids (n-3 PUFAs) are essential for the functional maturation of the brain. Westernization of dietary habits in both developed and developing countries is accompanied by a progressive reduction in dietary intake of n-3 PUFAs. Low maternal intake of n-3 PUFAs has been linked to neurodevelopmental diseases in Humans. However, the n-3 PUFAs deficiency-mediated mechanisms affecting the development of the central nervous system are poorly understood. Active microglial engulfment of syna ...[more]