Ontology highlight
ABSTRACT:
SUBMITTER: Zhang M
PROVIDER: S-EPMC7708432 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Zhang Mingxing M Zhang Ji J Wang Yibo Y Wang Jie J Achimovich Alecia M AM Acton Scott T ST Gahlmann Andreas A
Nature communications 20201201 1
Fluorescence microscopy enables spatial and temporal measurements of live cells and cellular communities. However, this potential has not yet been fully realized for investigations of individual cell behaviors and phenotypic changes in dense, three-dimensional (3D) bacterial biofilms. Accurate cell detection and cellular shape measurement in densely packed biofilms are challenging because of the limited resolution and low signal to background ratios (SBRs) in fluorescence microscopy images. In t ...[more]