Association of Use of a Meningococcus Group B Vaccine With Group B Invasive Meningococcal Disease Among Children in Portugal.

ABSTRACT:

Importance

A 4-component meningococcus group B vaccine (4CMenB) is the only vaccine in use to prevent group B invasive meningococcal disease in young children, but no matched controlled studies have evaluated it.

Objective

To determine the association between receipt of 4CMenB and invasive group B meningococcal disease.

Design, setting, and participants

Matched incidence density case-control study. Patients presenting from October 2014 to March 2019 were ascertained, with follow-up until death or discharge (last follow-up in June 2019) in 31 pediatric services in Portugal. Children and adolescent residents in Portugal with laboratory-confirmed invasive meningococcal disease were included. Controls, usually 2 per case, with unrelated conditions who were at the same hos

SUBMITTER: Rodrigues FMP 

PROVIDER: S-EPMC7709085 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature