Ontology highlight
ABSTRACT:
SUBMITTER: Desai N
PROVIDER: S-EPMC7725958 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Nature communications 20201209 1
The relationship of SARS-CoV-2 pulmonary infection and severity of disease is not fully understood. Here we show analysis of autopsy specimens from 24 patients who succumbed to SARS-CoV-2 infection using a combination of different RNA and protein analytical platforms to characterize inter-patient and intra-patient heterogeneity of pulmonary virus infection. There is a spectrum of high and low virus cases associated with duration of disease. High viral cases have high activation of interferon pat ...[more]