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Relationship of Telomere Length to Fat Redistribution in HIV.


ABSTRACT: Persons with HIV demonstrate increased risk for aging-associated complications and have reduced telomere length (TL) compared with age-matched persons without HIV. Our data show that greater visceral fat is related to reduced TL in HIV, independent of age and smoking. Fat redistribution may be a relevant mediator of TL attrition in HIV.

SUBMITTER: Iyengar S 

PROVIDER: S-EPMC7733235 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Relationship of Telomere Length to Fat Redistribution in HIV.

Iyengar Sanjna S   Cȏté Hélène C F HCF   Fitch Kathleen V KV   Torriani Martin M   Feldpausch Meghan M   Srinivasa Suman S  

Open forum infectious diseases 20201027 12


Persons with HIV demonstrate increased risk for aging-associated complications and have reduced telomere length (TL) compared with age-matched persons without HIV. Our data show that greater visceral fat is related to reduced TL in HIV, independent of age and smoking. Fat redistribution may be a relevant mediator of TL attrition in HIV. ...[more]

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