Ontology highlight
ABSTRACT:
SUBMITTER: Shuvalov O
PROVIDER: S-EPMC7733513 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Shuvalov Oleg O Kizenko Alyona A Petukhov Alexey A Fedorova Olga O Daks Alexandra A Bottrill Andrew A Snezhkina Anastasiya V AV Kudryavtseva Anna V AV Barlev Nikolai N
Cell death & disease 20201211 12
SEMG1 and SEMG2 genes belong to the family of cancer-testis antigens (CTAs), whose expression normally is restricted to male germ cells but is often restored in various malignancies. High levels of SEMG1 and SEMG2 expression are detected in prostate, renal, and lung cancer as well as hemoblastosis. However, the functional importance of both SEMGs proteins in human neoplasms is still largely unknown. In this study, by using a combination of the bioinformatics and various cellular and molecular as ...[more]