Ontology highlight
ABSTRACT:
SUBMITTER: Mestre MR
PROVIDER: S-EPMC7736814 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Mestre Mario Rodríguez MR González-Delgado Alejandro A Gutiérrez-Rus Luis I LI Martínez-Abarca Francisco F Toro Nicolás N
Nucleic acids research 20201201 22
Bacterial retrons consist of a reverse transcriptase (RT) and a contiguous non-coding RNA (ncRNA) gene. One third of annotated retrons carry additional open reading frames (ORFs), the contribution and significance of which in retron biology remains to be determined. In this study we developed a computational pipeline for the systematic prediction of genes specifically associated with retron RTs based on a previously reported large dataset representative of the diversity of prokaryotic RTs. We fo ...[more]