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ABSTRACT: Background
While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established.Methods
We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health and Demographic Surveillance System cohort.Results
The annual crude mortality rate per 1000 population for podoconiosis patients was 28.7 (95% confidence interval [CI] 17.3 to 44.8; n=663) while that of the general population was 2.8 (95% CI 2.3 to 3.4; n=44 095). The overall SMR for the study period was 6.0 (95% CI 3.6 to 9.4).Conclusions
Podoconiosis patients experience elevated mortality compared with the general population and further research is required to understand the reasons.
SUBMITTER: Masraf H
PROVIDER: S-EPMC7738655 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Masraf Hannah H Azemeraw Temesgen T Molla Meseret M Jones Christopher Iain CI Bremner Stephen S Ngari Moses M Berkley James A JA Kivaya Esther E Fegan Greg G Tamiru Abreham A Kelemework Abebe A Lang Trudie T Newport Melanie J MJ Davey Gail G
Transactions of the Royal Society of Tropical Medicine and Hygiene 20201201 12
<h4>Background</h4>While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established.<h4>Methods</h4>We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health and Demographic Surveillance System cohort.<h4>Results</h4>The annual crude mortality rate per 1000 population for podoconiosis patients was 28.7 (95% confidence interval [CI] 17.3 to 44 ...[more]