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Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts.


ABSTRACT:

Background

While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established.

Methods

We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health and Demographic Surveillance System cohort.

Results

The annual crude mortality rate per 1000 population for podoconiosis patients was 28.7 (95% confidence interval [CI] 17.3 to 44.8; n=663) while that of the general population was 2.8 (95% CI 2.3 to 3.4; n=44 095). The overall SMR for the study period was 6.0 (95% CI 3.6 to 9.4).

Conclusions

Podoconiosis patients experience elevated mortality compared with the general population and further research is required to understand the reasons.

SUBMITTER: Masraf H 

PROVIDER: S-EPMC7738655 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Publications

Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts.

Masraf Hannah H   Azemeraw Temesgen T   Molla Meseret M   Jones Christopher Iain CI   Bremner Stephen S   Ngari Moses M   Berkley James A JA   Kivaya Esther E   Fegan Greg G   Tamiru Abreham A   Kelemework Abebe A   Lang Trudie T   Newport Melanie J MJ   Davey Gail G  

Transactions of the Royal Society of Tropical Medicine and Hygiene 20201201 12


<h4>Background</h4>While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established.<h4>Methods</h4>We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health and Demographic Surveillance System cohort.<h4>Results</h4>The annual crude mortality rate per 1000 population for podoconiosis patients was 28.7 (95% confidence interval [CI] 17.3 to 44  ...[more]

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