Benchmarking Orthogroup Inference Accuracy: Revisiting Orthobench.
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ABSTRACT:
SUBMITTER: Emms DM
PROVIDER: S-EPMC7738749 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
Benchmarking Orthogroup Inference Accuracy: Revisiting Orthobench.
Emms David M DM Kelly Steven S
Genome biology and evolution 20201201 12
Orthobench is the standard benchmark to assess the accuracy of orthogroup inference methods. It contains 70 expert-curated reference orthogroups (RefOGs) that span the Bilateria and cover a range of different challenges for orthogroup inference. Here, we leveraged improvements in tree inference algorithms and computational resources to reinterrogate these RefOGs and carry out an extensive phylogenetic delineation of their composition. This phylogenetic revision altered the membership of 31 of th ...[more]
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