Identification of an inhibitory neuron subtype, the L-stellate cell of the cochlear nucleus.
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ABSTRACT:
SUBMITTER: Ngodup T
PROVIDER: S-EPMC7744103 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
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Identification of an inhibitory neuron subtype, the L-stellate cell of the cochlear nucleus.
Ngodup Tenzin T Romero Gabriel E GE Trussell Laurence O LO
eLife 20201103
Auditory processing depends upon inhibitory signaling by interneurons, even at its earliest stages in the ventral cochlear nucleus (VCN). Remarkably, to date only a single subtype of inhibitory neuron has been documented in the VCN, a projection neuron termed the D-stellate cell. With the use of a transgenic mouse line, optical clearing, and imaging techniques, combined with electrophysiological tools, we revealed a population of glycinergic cells in the VCN distinct from the D-stellate cell. Th ...[more]
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