Ontology highlight
ABSTRACT:
SUBMITTER: Zhu T
PROVIDER: S-EPMC7753234 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Zhu Tianyu T Wang Zhuoyin Z Wang Guojun G Hu Zhihao Z Ding Hengxuan H Li Ruixin R Sun Junfeng J
Journal of advanced research 20200624
LncRNA (Long non-coding RNA) ZFAS1 (zinc finger antisense 1) functions as the oncogene in multiple cancers, including gastric cancer. However, its function and underlying mechanism in the GCA (gastric cardia adenocarcinoma), the most aggressive type of gastric cancer, remain unknown. We demonstrated here that the LncRNA ZFAS1 was up-regulated in GCA tissues. Furthermore, the elevated level of ZFAS1 was significantly associated with the GCA metastasis and cancer recurrence. It was also demonstrat ...[more]