Ontology highlight
ABSTRACT:
SUBMITTER: Pan JW
PROVIDER: S-EPMC7755902 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Pan Jia-Wern JW Zabidi Muhammad Mamduh Ahmad MMA Ng Pei-Sze PS Meng Mei-Yee MY Hasan Siti Norhidayu SN Sandey Bethan B Sammut Stephen-John SJ Yip Cheng-Har CH Rajadurai Pathmanathan P Rueda Oscar M OM Caldas Carlos C Chin Suet-Feung SF Teo Soo-Hwang SH
Nature communications 20201222 1
Molecular profiling of breast cancer has enabled the development of more robust molecular prognostic signatures and therapeutic options for breast cancer patients. However, non-Caucasian populations remain understudied. Here, we present the mutational, transcriptional, and copy number profiles of 560 Malaysian breast tumours and a comparative analysis of breast cancers arising in Asian and Caucasian women. Compared to breast tumours in Caucasian women, we show an increased prevalence of HER2-enr ...[more]