Ontology highlight
ABSTRACT:
SUBMITTER: Lagos-Cabre R
PROVIDER: S-EPMC7758162 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Lagos-Cabré Raul R Ivanova Adelina A Taylor Colin W CW
Cell reports 20201201 11
The mitotic spindle distributes chromosomes evenly to daughter cells during mitosis. The orientation of the spindle, guided by internal and external cues, determines the axis of cell division and thereby contributes to tissue morphogenesis. Progression through mitosis requires local Ca<sup>2+</sup> signals at critical steps, and because store-operated Ca<sup>2+</sup> entry is inhibited during mitosis, those signals probably require Ca<sup>2+</sup> release through inositol 1,4,5-trisphosphate rec ...[more]