Ontology highlight
ABSTRACT:
SUBMITTER: Abdullah SW
PROVIDER: S-EPMC7760909 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Abdullah Sahibzada Waheed SW Han Shichong S Wu Jin'en J Zhang Yun Y Bai Manyuan M Jin Ye Y Zhi Xiaoying X Guan Junyong J Sun Shiqi S Guo Huichen H
Viruses 20201125 12
DEAD-box helicase 23 (DDX23) is a host nuclear helicase, which is a part of the spliceosomal complex and involved in pre-mRNA splicing. To investigate whether DDX23, an internal ribosomal entry sites transacting factor (ITAF) affects foot-and-mouth disease virus (FMDV) replication and translation through internal ribosome entry site (IRES)-dependent manner. For this, we utilized a pull-down assay, Western blotting, quantitative real-time PCR, confocal microscopy, overexpression and small interfe ...[more]