Cytokines and Transgenic Matrix in Autoimmune Diseases: Similarities and Differences.
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SUBMITTER: Szewczak L
PROVIDER: S-EPMC7761121 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
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Cytokines and Transgenic Matrix in Autoimmune Diseases: Similarities and Differences.
Szewczak Ludmiła L Donskow-Łysoniewska Katarzyna K
Biomedicines 20201201 12
Autoimmune diseases are increasingly recognized as disease entities in which dysregulated cytokines contribute to tissue-specific inflammation. In organ-specific and multiorgan autoimmune diseases, the cytokine profiles show some similarities. Despite these similarities, the cytokines have different roles in the pathogenesis of different diseases. Altered levels or action of cytokines can result from changes in cell signaling. This article describes alterations in the JAK-STAT, TGF-β and NF-κB s ...[more]
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