Ontology highlight
ABSTRACT:
SUBMITTER: Bonfa G
PROVIDER: S-EPMC7761833 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Bonfá Giuliano G Blazquez-Roman Juan J Tarnai Rita R Siciliano Velia V
Vaccines 20201203 4
Engineered mammalian cells for medical purposes are becoming a clinically relevant reality thanks to advances in synthetic biology that allow enhanced reliability and safety of cell-based therapies. However, their application is still hampered by challenges including time-consuming design-and-test cycle iterations and costs. For example, in the field of cancer immunotherapy, CAR-T cells targeting CD19 have already been clinically approved to treat several types of leukemia, but their use in the ...[more]