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ABSTRACT:
SUBMITTER: Parveen S
PROVIDER: S-EPMC7763117 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Parveen Shaista S Kalsoom Saima S Bibi Rifhat R Asghar Ambreen A Hameed Abdul A Ahmed Waqar W Hassan Abbas A
Turkish journal of chemistry 20201216 6
The current investigation presents the synthesis, computational molecular-docking and biological activity studies of arylated thiazole coumarins. Aryl substituted thiazolyl coumarin derivatives were synthesized via Suzuki cross-coupling reaction. A detailed reaction condition optimization revealed that the Pd-PEPPSI-IPent precatalyst in only 2 mol% loading resulted in the desired product with high yield. The aim of this study was to examine the antimicrobial behavior of thiazole coumarin derivat ...[more]