Ontology highlight
ABSTRACT:
SUBMITTER: Maas MN
PROVIDER: S-EPMC7764450 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Maas Marijn N MN Hintzen Jordi C J JCJ Porzberg Miriam R B MRB Mecinović Jasmin J
International journal of molecular sciences 20201211 24
Trimethyllysine is an important post-translationally modified amino acid with functions in the carnitine biosynthesis and regulation of key epigenetic processes. Protein lysine methyltransferases and demethylases dynamically control protein lysine methylation, with each state of methylation changing the biophysical properties of lysine and the subsequent effect on protein function, in particular histone proteins and their central role in epigenetics. Epigenetic reader domain proteins can disting ...[more]