Ontology highlight
ABSTRACT:
SUBMITTER: Prieto-Bermejo R
PROVIDER: S-EPMC7776239 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Prieto-Bermejo Rodrigo R Romo-González Marta M Pérez-Fernández Alejandro A García-Tuñón Ignacio I Sánchez-Martín Manuel M Hernández-Hernández Ángel Á
Haematologica 20210101 1
The regulation of protein function by reversible oxidation is increasingly recognized as a key mechanism for the control of cellular signaling, modulating crucial biological processes such as cell differentiation. In this scenario, NADPH oxidases must occupy a prominent position. Our results show that hematopoietic stem and progenitor cells express three p22phox-dependent NADPH oxidases members (NOX1, NOX2 and NOX4). By deleting the p22phox coding gene (Cyba), here we have analyzed the importanc ...[more]