Ontology highlight
ABSTRACT:
SUBMITTER: Derks YHW
PROVIDER: S-EPMC7778589 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Derks Yvonne H W YHW Rijpkema Mark M Amatdjais-Groenen Helene I V HIV Kip Annemarie A Franssen Gerben M GM Sedelaar J P Michiel JPM Somford Diederik M DM Simons Michiel M Laverman Peter P Gotthardt Martin M Löwik Dennis W P M DWPM Lütje Susanne S Heskamp Sandra S
Theranostics 20210101 4
Incomplete resection of prostate cancer (PCa) occurs in 15%-50% of PCa patients. Disease recurrence negatively impacts oncological outcome. The use of radio-, fluorescent-, or photosensitizer-labeled ligands to target the prostate-specific membrane antigen (PSMA) has become a well-established method for the detection and treatment of PCa. <b>Methods:</b> Here, we developed and characterized multimodal [<sup>111</sup>In]In-DOTA(GA)-IRDye700DX-PSMA ligands, varying in their molecular composition, ...[more]