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PSMA-targeted contrast agents for intraoperative imaging of prostate cancer.


ABSTRACT: Prostate-specific membrane antigen (PSMA) can serve as a molecular cell surface target for the detection and treatment of prostate cancer. Near-infrared (NIR) fluorescence imaging enables highly sensitive, rapid, and non-radioactive imaging of PSMA, though specific targeting still remains a challenge because no optimized contrast agents exist.

SUBMITTER: Bao K 

PROVIDER: S-EPMC5728657 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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PSMA-targeted contrast agents for intraoperative imaging of prostate cancer.

Bao Kai K   Lee Jeong Heon JH   Kang Homan H   Park G Kate GK   El Fakhri Georges G   Choi Hak Soo HS  

Chemical communications (Cambridge, England) 20170113 10


Prostate-specific membrane antigen (PSMA) can serve as a molecular cell surface target for the detection and treatment of prostate cancer. Near-infrared (NIR) fluorescence imaging enables highly sensitive, rapid, and non-radioactive imaging of PSMA, though specific targeting still remains a challenge because no optimized contrast agents exist. ...[more]

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