Ontology highlight
ABSTRACT:
SUBMITTER: Stortz F
PROVIDER: S-EPMC7778913 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Nucleic acids research 20210101 D1
With ongoing development of the CRISPR/Cas programmable nuclease system, applications in the area of in vivo therapeutic gene editing are increasingly within reach. However, non-negligible off-target effects remain a major concern for clinical applications. Even though a multitude of off-target cleavage datasets have been published, a comprehensive, transparent overview tool has not yet been established. Here, we present crisprSQL (http://www.crisprsql.com), an interactive and bioinformatically ...[more]