Ontology highlight
ABSTRACT:
SUBMITTER: Wang B
PROVIDER: S-EPMC7783358 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Wang Bing B Wang Xiaowei X Tong Xing X Zhang Yingang Y
Frontiers in genetics 20201222
Osteosarcoma is a primary tumor of bone and its incidence is increasing. Schisandrin B (Sch B), a generally used lignan in Chinese medicine, has been found to repress cancer progression. This study aims to reveal the effects and regulatory mechanism of Sch B in the viability, apoptosis and migration of osteosarcoma cells. In this study, we found circ_0009112 expression was higher and miR-708-5p expression was lower in SaOS2 and U2OS cells than in hFOB1.19 cells. Circ_0009112 expression was downr ...[more]