Ontology highlight
ABSTRACT:
SUBMITTER: Domart F
PROVIDER: S-EPMC7787660 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Domart Florelle F Cloetens Peter P Roudeau Stéphane S Carmona Asuncion A Verdier Emeline E Choquet Daniel D Ortega Richard R
eLife 20201208
Zinc and copper are involved in neuronal differentiation and synaptic plasticity but the molecular mechanisms behind these processes are still elusive due in part to the difficulty of imaging trace metals together with proteins at the synaptic level. We correlate stimulated-emission-depletion microscopy of proteins and synchrotron X-ray fluorescence imaging of trace metals, both performed with 40 nm spatial resolution, on primary rat hippocampal neurons. We reveal the co-localization at the nano ...[more]