Dataset Information

Long-term effects of fine particulate matter exposure on the progression of arterial stiffness.

ABSTRACT:

Background

Prior studies have investigated the association of PM_2.5 exposure with arterial stiffness measured by ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV), of which conclusions are inconsistent. Moreover, limited evidence is available on the contributory role of PM_2.5 exposure on the arterial stiffness index.

Methods

We used the population data from the Beijing Health Management Cohort and conducted a longitudinal analysis. The annual average concentration of PM_2.5 for 35 air pollutant monitoring sites in Beijing from 2014 to 2018 was used to estimate individual exposure by different interpolation methods. Multivariate logistic regression and linear regression were conducted to assess the association of annual average PM_2.5 concentration with the incidence of higher baPWV, the progression of ABI, and baPWV, respectively.

Results

The association between PM_2.5 exposure and incidence of higher baPWV was not significant (OR = 1.11, 95% CI: 0.82-1.50, P = 0.497). There was -?0.16% (95% CI: -?0.43-0.11%) decrease in ABI annually and 1.04% (95% CI: 0.72-1.37%) increase in baPWV annually with each increment of 10??g/m³ average PM_2.5 concentration.

Conclusions

Long-term exposure to PM_2.5 was associated with the progression of arterial stiffness in Beijing. This study suggests that improvement of air quality may help to prevent arterial stiffness.

SUBMITTER: Sun D

PROVIDER: S-EPMC7789369 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Publications

Long-term effects of fine particulate matter exposure on the progression of arterial stiffness.

Sun Dianqin D Liu Yue Y Zhang Jie J Liu Jia J Wu Zhiyuan Z Liu Mengyang M Li Xia X Guo Xiuhua X Tao Lixin L

Environmental health : a global access science source 20210106 1

<h4>Background</h4>Prior studies have investigated the association of PM<sub>2.5</sub> exposure with arterial stiffness measured by ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV), of which conclusions are inconsistent. Moreover, limited evidence is available on the contributory role of PM<sub>2.5</sub> exposure on the arterial stiffness index.<h4>Methods</h4>We used the population data from the Beijing Health Management Cohort and conducted a longitudinal analysis. The ...[more]

PMID: 33407540

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Dataset Information

Long-term effects of fine particulate matter exposure on the progression of arterial stiffness.

Background

Methods

Results

Conclusions

Publications

Long-term effects of fine particulate matter exposure on the progression of arterial stiffness.

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