Identification of differentially expressed proteins and clinicopathological significance of HMGB2 in cervical cancer.
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ABSTRACT:
SUBMITTER: Han X
PROVIDER: S-EPMC7789524 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
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Identification of differentially expressed proteins and clinicopathological significance of HMGB2 in cervical cancer.
Han Xiao X Zhong Siyi S Zhang Pengnan P Liu Yanmei Y Shi Sangsang S Wu Congquan C Gao Shujun S
Clinical proteomics 20210106 1
To investigate the complexity of proteomics in cervical cancer tissues, we used isobaric tags for relative and absolute quantitation (iTRAQ)-based mass spectrometry analysis on a panel of normal cervical tissues (N), high-grade squamous intraepithelial lesion tissues (HSIL) and cervical cancer tissues (CC). Total 72 differentially expressed proteins were identified both in CC vs N and CC vs HSIL. The expression of HMGB2 was markedly higher in CC than that in HSIL and N. High HMGB2 expression was ...[more]
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