Ontology highlight
ABSTRACT:
SUBMITTER: Franzini R
PROVIDER: S-EPMC7796420 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Franzini Roberta R Pierini Marco M Mazzanti Andrea A Iazzetti Antonia A Ciogli Alessia A Villani Claudio C
International journal of molecular sciences 20201225 1
The presence of stereogenic elements is a common feature in pharmaceutical compounds, and affording optically pure stereoisomers is a frequent issue in drug design. In this context, the study of the chiral molecular recognition mechanism fundamentally supports the understanding and optimization of chromatographic separations with chiral stationary phases. We investigated, with molecular docking, the interactions between the chiral HPLC selector Whelk-O1 and the stereoisomers of two bioactive com ...[more]