Ontology highlight
ABSTRACT:
SUBMITTER: Watson JL
PROVIDER: S-EPMC7802367 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Watson Joseph L JL Aich Samya S Oller-Salvia Benjamí B Drabek Andrew A AA Blacklow Stephen C SC Chin Jason J Derivery Emmanuel E
The Journal of cell biology 20210201 2
Protein micropatterning allows proteins to be precisely deposited onto a substrate of choice and is now routinely used in cell biology and in vitro reconstitution. However, drawbacks of current technology are that micropatterning efficiency can be variable between proteins and that proteins may lose activity on the micropatterns. Here, we describe a general method to enable micropatterning of virtually any protein at high specificity and homogeneity while maintaining its activity. Our method is ...[more]