Ontology highlight
ABSTRACT:
SUBMITTER: Wood ET
PROVIDER: S-EPMC7804323 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Wood Emily T ET Cummings Kaitlin K KK Jung Jiwon J Patterson Genevieve G Okada Nana N Guo Jia J O'Neill Joseph J Dapretto Mirella M Bookheimer Susan Y SY Green Shulamite A SA
Translational psychiatry 20210112 1
Sensory over-responsivity (SOR), extreme sensitivity to or avoidance of sensory stimuli (e.g., scratchy fabrics, loud sounds), is a highly prevalent and impairing feature of neurodevelopmental disorders such as autism spectrum disorders (ASD), anxiety, and ADHD. Previous studies have found overactive brain responses and reduced modulation of thalamocortical connectivity in response to mildly aversive sensory stimulation in ASD. These findings suggest altered thalamic sensory gating which could b ...[more]