Ontology highlight
ABSTRACT:
SUBMITTER: Bediaga NG
PROVIDER: S-EPMC7804404 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Bediaga Naiara G NG Coughlan Hannah D HD Johanson Timothy M TM Garnham Alexandra L AL Naselli Gaetano G Schröder Jan J Fearnley Liam G LG Bandala-Sanchez Esther E Allan Rhys S RS Smyth Gordon K GK Harrison Leonard C LC
Scientific reports 20210112 1
Remodelling of chromatin architecture is known to regulate gene expression and has been well characterized in cell lineage development but less so in response to cell perturbation. Activation of T cells, which triggers extensive changes in transcriptional programs, serves as an instructive model to elucidate how changes in chromatin architecture orchestrate gene expression in response to cell perturbation. To characterize coordinate changes at different levels of chromatin architecture, we analy ...[more]