Ontology highlight
ABSTRACT:
SUBMITTER: Shen Z
PROVIDER: S-EPMC7806625 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Shen Zhou Z Teo Colin Zhi Wei CZW Ayyer Kartik K Loh N Duane ND
Scientific reports 20210113 1
We propose an encryption-decryption framework for validating diffraction intensity volumes reconstructed using single-particle imaging (SPI) with X-ray free-electron lasers (XFELs) when the ground truth volume is absent. This conceptual framework exploits each reconstructed volumes' ability to decipher latent variables (e.g. orientations) of unseen sentinel diffraction patterns. Using this framework, we quantify novel measures of orientation disconcurrence, inconsistency, and disagreement betwee ...[more]