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Multi-center evaluation of dose conformity in stereotactic body radiotherapy.


ABSTRACT:

Background and purpose

Stereotactic body radiotherapy (SBRT) is an emerging technique for treating oligometastases, but limited data is available on what plan quality is achievable for a range of modalities and clinical sites.

Methods

SBRT plans for lung, spine, bone, adrenal, liver and node sites from 17 participating centers were reviewed. Centers used various delivery techniques including static and rotational intensity-modulation and multiple non-coplanar beams. Plans were split into lung and other body sites and evaluated with different plan quality metrics, including two which are independent of target coverage; "prescription dose spillage" (PDS) and "modified gradient index" (MGI). These were compared to constraints from the ROSEL and RTOG 0813 clinical trials.

Results

Planning target volume (PTV) coverage was compromised (PTV V100%?3.

Conclusions

Updated guidance for lung and other body site SBRT plan quality using the PDS and MGI metrics is presented.

SUBMITTER: Lee J 

PROVIDER: S-EPMC7807546 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Publications

Multi-center evaluation of dose conformity in stereotactic body radiotherapy.

Lee Jonny J   Dean Christopher C   Patel Rushil R   Webster Gareth G   Eaton David J DJ  

Physics and imaging in radiation oncology 20190701


<h4>Background and purpose</h4>Stereotactic body radiotherapy (SBRT) is an emerging technique for treating oligometastases, but limited data is available on what plan quality is achievable for a range of modalities and clinical sites.<h4>Methods</h4>SBRT plans for lung, spine, bone, adrenal, liver and node sites from 17 participating centers were reviewed. Centers used various delivery techniques including static and rotational intensity-modulation and multiple non-coplanar beams. Plans were spl  ...[more]

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