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BaSDAS: a web-based pooled CRISPR-Cas9 knockout screening data analysis system.

ABSTRACT: We developed the BaSDAS (Barcode-Seq Data Analysis System), a GUI-based pooled knockout screening data analysis system, to facilitate the analysis of pooled knockout screen data easily and effectively by researchers with limited bioinformatics skills. The BaSDAS supports the analysis of various pooled screening libraries, including yeast, human, and mouse libraries, and provides many useful statistical and visualization functions with a user-friendly web interface for convenience. We expect that BaSDAS will be a useful tool for the analysis of genome-wide screening data and will support the development of novel drugs based on functional genomics information.

SUBMITTER: Park YK

PROVIDER: S-EPMC7808871 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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BaSDAS: a web-based pooled CRISPR-Cas9 knockout screening data analysis system.

Park Young-Kyu YK Yoon Byoung-Ha BH Park Seung-Jin SJ Kim Byung Kwon BK Kim Seon-Young SY

Genomics & informatics 20201211 4

We developed the BaSDAS (Barcode-Seq Data Analysis System), a GUI-based pooled knockout screening data analysis system, to facilitate the analysis of pooled knockout screen data easily and effectively by researchers with limited bioinformatics skills. The BaSDAS supports the analysis of various pooled screening libraries, including yeast, human, and mouse libraries, and provides many useful statistical and visualization functions with a user-friendly web interface for convenience. We expect that ...[more]

PMID: 33412762

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