Ontology highlight
ABSTRACT:
SUBMITTER: Gaspar RS
PROVIDER: S-EPMC7809045 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Gaspar Renato S RS Unsworth Amanda J AJ Al-Dibouni Alaa A Bye Alexander P AP Sage Tanya T Stewart Michelle M Wells Sara S Cox Roger D RD Gibbins Jonathan M JM Sellayah Dyan D E Hughes Craig C
Scientific reports 20210114 1
Maternal over-nutrition increases the risk of diabetes and cardiovascular events in offspring. While prominent effects on cardiovascular health are observed, the impact on platelet physiology has not been studied. Here, we examined whether maternal high-fat diet (HF) ingestion affects the platelet function in lean and obese offspring. C57BL6/N mice dams were given a HF or control (C) diet for 8 weeks before and during pregnancy. Male and female offspring received C or HF diets for 26 weeks. Expe ...[more]