Ontology highlight
ABSTRACT:
SUBMITTER: Babu ST
PROVIDER: S-EPMC6237468 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Babu Sarah Thomas ST Niu Xinying X Raetz Megan M Savani Rashmin C RC Hooper Lora V LV Mirpuri Julie J
JCI insight 20181004 19
Maternal obesity and a high-fat diet (HFD) during the perinatal period have documented short- and long-term adverse outcomes for offspring. However, the mechanisms of maternal HFD effects on neonatal offspring are unclear. While the effects of maternal HFD exposure during pregnancy on the offspring are increasingly being appreciated, we do not know if maternal HFD alters the microbiota or affects neonatal susceptibility to inflammatory conditions, nor the mechanisms involved. In this study, we s ...[more]