Ontology highlight
ABSTRACT:
SUBMITTER: Szabo LE
PROVIDER: S-EPMC7809465 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Szabó Lilla E LE Marcello G Mark GM Süth Miklós M Sótonyi Péter P Rácz Bence B
Scientific reports 20210114 1
Dendritic spines are the primary sites of excitatory transmission in the mammalian brain. Spines of cerebellar Purkinje Cells (PCs) are plastic, but they differ from forebrain spines in a number of important respects, and the mechanisms of spine plasticity differ between forebrain and cerebellum. Our previous studies indicate that in hippocampal spines cortactin-a protein that stabilizes actin branch points-resides in the spine core, avoiding the spine shell. To see whether the distribution of c ...[more]