Strontium ions protect hearts against myocardial ischemia/reperfusion injury.
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ABSTRACT:
SUBMITTER: Xing M
PROVIDER: S-EPMC7810382 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Publications
Strontium ions protect hearts against myocardial ischemia/reperfusion injury.
Xing Min M Jiang Yun Y Bi Wei W Gao Long L Zhou Yan-Ling YL Rao Sen-Le SL Ma Ling-Ling LL Zhang Zhao-Wenbin ZW Yang Huang-Tian HT Chang Jiang J
Science advances 20210115 3
Timely restoration of blood supply following myocardial infarction is critical to save the infarcted myocardium, while reperfusion would cause additional damage. Strontium ions have been shown to promote angiogenesis, but it is unknown whether they can save the damaged myocardium. We report that myocardial ischemia/reperfusion (I/R)-induced functional deterioration and scar formation were notably attenuated by injection of strontium ion-containing composite hydrogels into murine infarcted myocar ...[more]
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