Ontology highlight
ABSTRACT:
SUBMITTER: Yuan X
PROVIDER: S-EPMC4461317 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Yuan Xuan X Niu Hai-tao HT Wang Peng-long PL Lu Jie J Zhao Hong H Liu Shi-han SH Zheng Qiu-sheng QS Li Chang-gui CG
PloS one 20150609 6
Flavonoids are important components of 'functional foods', with beneficial effects on cardiovascular function. The present study was designed to investigate whether licochalcone D (LD) could be a cardioprotective agent in ischemia/reperfusion (I/R) injury and to shed light on its possible mechanism. Compared with the I/R group, LD treatment enhanced myocardial function (increased LVDP, dp/dtmax, dp/dtmin, HR and CR) and suppressed cardiac injury (decreased LDH, CK and myocardial infarct size). M ...[more]