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Interpopulation differences of retroduplication variations (RDVs) in rice retrogenes and their phenotypic correlations.


ABSTRACT: Retroduplication variation (RDV), a type of retrocopy polymorphism, is considered to have essential biological significance, but its effect on gene function and species phenotype is still poorly understood. To this end, we analyzed the retrocopies and RDVs in 3,010 rice genomes. We calculated the RDV frequencies in the genome of each rice population; detected the mutated, ancestral and expressed retrogenes in rice genomes; and analyzed their RDV influence on rice phenotypic traits. Collectively, 73 RDVs were identified, and 14 RDVs in ancestral retrogenes can significantly affect rice phenotypes. Our research reveals that RDV plays an important role in rice migration, domestication and evolution. We think that RDV is a good molecular breeding marker candidate. To our knowledge, this is the first study on the relationship between retrogene function, expression, RDV and species phenotype.

SUBMITTER: Zeng H 

PROVIDER: S-EPMC7811064 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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Interpopulation differences of retroduplication variations (RDVs) in rice retrogenes and their phenotypic correlations.

Zeng Haiyue H   Chen Xingyu X   Chen Xingyu X   Li Hongbo H   Zhang Jun J   Wei Zhaoyuan Z   Wang Yi Y  

Computational and structural biotechnology journal 20210105


Retroduplication variation (RDV), a type of retrocopy polymorphism, is considered to have essential biological significance, but its effect on gene function and species phenotype is still poorly understood. To this end, we analyzed the retrocopies and RDVs in 3,010 rice genomes. We calculated the RDV frequencies in the genome of each rice population; detected the mutated, ancestral and expressed retrogenes in rice genomes; and analyzed their RDV influence on rice phenotypic traits. Collectively,  ...[more]

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