Ontology highlight
ABSTRACT:
SUBMITTER: Yang L
PROVIDER: S-EPMC7812262 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Yang Lehe L Zhu Tianru T Ye Hua H Shen Yili Y Li Zhiping Z Chen Luye L Wang Canwei C Chen Xia X Zhao Haiyang H Xiang Youqun Y Xiao Zhongxiang Z Zhao Chengguang C Li Jifa J Hu Wanle W
Journal of cellular and molecular medicine 20201201 2
Colorectal cancer (CRC) accounts for about 10% of all annually diagnosed cancers and cancer-related deaths worldwide. STAT3 plays a vital role in the occurrence and development of tumours. Gracillin has shown a significant antitumour activity in tumours, but its mechanism remains unknown. The human CRC cell lines HCT116, RKO, and SW480 and immunodeficient mice were used as models to study the effects of gracillin on cell proliferation, migration and apoptosis. These were evaluated by cell viabil ...[more]