Dataset Information
Predictive factors of posttreatment fracture by definitive radiotherapy for uterine cervical cancer.
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ABSTRACT: Purpose
Fractures are known to shorten life expectancy and worsen the quality of life. The risk of fractures after radiation therapy in cervical cancer patients is known to be multifactorial. In this study, we examined risk factors for fractures in cervical cancer patients, especially by evaluating bone densities and DVH parameters for fractured bones.Materials and methods
For 42 patients, clinical characteristics, pretreatment CT bone densities, and radiation dose were compared between patients with and without fractures.Results
Posttreatment fractures occurred in 25 bones among ten patients. Pretreatment CT bone densities were significantly lower in patients with fractures (P?ConclusionPretreatment CT densities of spinal and pelvic bones, which may reflect osteoporosis, have a significant impact on the risk for posttreatment fractures.
SUBMITTER: Ishikawa K
PROVIDER: S-EPMC7813741 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Publications
Predictive factors of posttreatment fracture by definitive radiotherapy for uterine cervical cancer.
Japanese journal of radiology 20200907 1
<h4>Purpose</h4>Fractures are known to shorten life expectancy and worsen the quality of life. The risk of fractures after radiation therapy in cervical cancer patients is known to be multifactorial. In this study, we examined risk factors for fractures in cervical cancer patients, especially by evaluating bone densities and DVH parameters for fractured bones.<h4>Materials and methods</h4>For 42 patients, clinical characteristics, pretreatment CT bone densities, and radiation dose were compared ...[more]