Unknown

Dataset Information

0

The biological pathways of Alzheimer disease: a review.


ABSTRACT: Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older people, which severely impairs patients' quality of life. In the recent years, the number of affected individuals has seen a rapid increase. It is estimated that up to 107 million subjects will be affected by 2050 worldwide. Research in this area has revealed a lot about the biological and environmental underpinnings of Alzheimer, especially its correlation with ?-Amyloid and Tau related mechanics; however, the precise molecular events and biological pathways behind the disease are yet to be discovered. In this review, we focus our attention on the biological mechanics that may lie behind Alzheimer development. In particular, we briefly describe the genetic elements and discuss about specific biological processes potentially associated with the disease.

SUBMITTER: Calabro M 

PROVIDER: S-EPMC7815481 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

altmetric image

Publications

The biological pathways of Alzheimer disease: a review.

Calabrò Marco M   Rinaldi Carmela C   Santoro Giuseppe G   Crisafulli Concetta C  

AIMS neuroscience 20201216 1


Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older people, which severely impairs patients' quality of life. In the recent years, the number of affected individuals has seen a rapid increase. It is estimated that up to 107 million subjects will be affected by 2050 worldwide. Research in this area has revealed a lot about the biological and environmental underpinnings of Alzheimer, especially its correlation with β-Amyloid and Tau related mechanics; however, the  ...[more]

Similar Datasets

| S-EPMC7238917 | biostudies-literature
| S-EPMC6759853 | biostudies-literature
| S-EPMC2906579 | biostudies-literature
2023-09-19 | GSE180968 | GEO
| S-EPMC8698767 | biostudies-literature
| S-EPMC7736722 | biostudies-literature
| S-EPMC8574196 | biostudies-literature
| S-EPMC6137293 | biostudies-literature
| S-EPMC3961547 | biostudies-literature
2013-03-29 | E-GEOD-45596 | biostudies-arrayexpress