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The influence of animal species, gender and tissue on the structural, biophysical, biochemical and biological properties of collagen sponges.

ABSTRACT: Although collagen type I is extensively used in biomedicine, no study to-date has assessed how the properties of the produced scaffolds are affected as a function of species, gender and tissue from which the collagen was extracted. Herein, we extracted and characterised collagen from porcine and bovine, male and female and skin and tendon tissues and we subsequently fabricated and assessed the structural, biophysical, biochemical and biological properties of collagen sponges. All collagen preparations were of similar purity and free-amine content (p?>?0.05). In general, the porcine groups yielded more collagen; had higher (p?

SUBMITTER: Sorushanova A

PROVIDER: S-EPMC7819930 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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The influence of animal species, gender and tissue on the structural, biophysical, biochemical and biological properties of collagen sponges.

Sorushanova Anna A Skoufos Ioannis I Tzora Athina A Mullen Anne Maria AM Zeugolis Dimitrios I DI

Journal of materials science. Materials in medicine 20210121 1

Although collagen type I is extensively used in biomedicine, no study to-date has assessed how the properties of the produced scaffolds are affected as a function of species, gender and tissue from which the collagen was extracted. Herein, we extracted and characterised collagen from porcine and bovine, male and female and skin and tendon tissues and we subsequently fabricated and assessed the structural, biophysical, biochemical and biological properties of collagen sponges. All collagen prepar ...[more]

PMID: 33475864

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