Unknown

Dataset Information

0

Copper-Catalyzed Oxidative Cross-Coupling of Electron-Deficient Polyfluorophenylboronate Esters with Terminal Alkynes.

ABSTRACT: We report herein a mild procedure for the copper-catalyzed oxidative cross-coupling of electron-deficient polyfluorophenylboronate esters with terminal alkynes. This method displays good functional group tolerance and broad substrate scope, generating cross-coupled alkynyl(fluoro)arene products in moderate to excellent yields. Thus, it represents a simple alternative to the conventional Sonogashira reaction.

SUBMITTER: Liu Z 

PROVIDER: S-EPMC7821263 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Copper-Catalyzed Oxidative Cross-Coupling of Electron-Deficient Polyfluorophenylboronate Esters with Terminal Alkynes.

Liu Zhiqiang Z   Budiman Yudha P YP   Tian Ya-Ming YM   Friedrich Alexandra A   Huang Mingming M   Westcott Stephen A SA   Radius Udo U   Marder Todd B TB  

Chemistry (Weinheim an der Bergstrasse, Germany) 20201109 71

We report herein a mild procedure for the copper-catalyzed oxidative cross-coupling of electron-deficient polyfluorophenylboronate esters with terminal alkynes. This method displays good functional group tolerance and broad substrate scope, generating cross-coupled alkynyl(fluoro)arene products in moderate to excellent yields. Thus, it represents a simple alternative to the conventional Sonogashira reaction. ...[more]

Similar Datasets

Unknown Copper-catalyzed oxidative cross-dehydrogenative coupling of 2H-chromenes and terminal alkynes.
| S-EPMC6051884 | biostudies-literature
Unknown Selective Manganese-Catalyzed Dimerization and Cross-Coupling of Terminal Alkynes.
| S-EPMC8185884 | biostudies-literature
Unknown Copper-catalyzed enantioselective Sonogashira-type oxidative cross-coupling of unactivated C(sp<sup>3</sup>)-H bonds with alkynes.
| S-EPMC6908613 | biostudies-literature
Unknown Gold-catalyzed reaction of oxabicyclic alkenes with electron-deficient terminal alkynes to produce acrylate derivatives.
| S-EPMC3817539 | biostudies-literature
Unknown Copper catalyzed photoredox synthesis of α-keto esters, quinoxaline, and naphthoquinone: controlled oxidation of terminal alkynes to glyoxals.
| S-EPMC6167948 | biostudies-literature
Unknown Copper-catalyzed dehydrogenative borylation of terminal alkynes with pinacolborane.
| S-EPMC5308285 | biostudies-other
Unknown Direct Zinc(II)-Catalyzed Enantioconvergent Additions of Terminal Alkynes to ?-Keto Esters.
| S-EPMC5554871 | biostudies-literature
Unknown Copper-catalyzed oxidative homo- and cross-coupling of Grignard reagents using diaziridinone.
| S-EPMC4260645 | biostudies-literature
Unknown Functionalization of remote C(sp3)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes.
| S-EPMC6972843 | biostudies-literature
Unknown Pd-Catalyzed Suzuki-Miyaura Cross-Coupling of Pentafluorophenyl Esters.
| S-EPMC6321476 | biostudies-literature