Ontology highlight
ABSTRACT:
SUBMITTER: Ruddraraju KV
PROVIDER: S-EPMC7822160 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Microorganisms 20201223 1
Tuberculosis (TB) is an airborne infectious disease caused by <i>Mycobacterium tuberculosis</i> (Mtb). According to the World Health Organization, an estimated 10 million people developed TB in 2018. The occurrence of drug-resistant TB demands therapeutic agents with novel mechanisms of action. Antivirulence is an alternative strategy that targets bacterial virulence factors instead of central growth pathways to treat disease. <i>Mycobacterium</i> protein tyrosine phosphatases, mPTPA and mPTPB, ...[more]