Ontology highlight
ABSTRACT:
SUBMITTER: Cho NY
PROVIDER: S-EPMC7823774 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Cho Nam-Yun NY Park Ji-Won JW Wen Xianyu X Shin Yun-Joo YJ Kang Jun-Kyu JK Song Sang-Hyun SH Kim Hwang-Phill HP Kim Tae-You TY Bae Jeong Mo JM Kang Gyeong Hoon GH
Diagnostics (Basel, Switzerland) 20201231 1
Cancer tissues have characteristic DNA methylation profiles compared with their corresponding normal tissues that can be utilized for cancer diagnosis with liquid biopsy. Using a genome-scale DNA methylation approach, we sought to identify a panel of DNA methylation markers specific for cell-free DNA (cfDNA) from patients with colorectal cancer (CRC). By comparing DNA methylomes between CRC and normal mucosal tissues or blood leukocytes, we identified eight cancer-specific methylated loci (<i>AD ...[more]