Favipiravir in Therapy of Viral Infections.
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ABSTRACT:
SUBMITTER: Lagocka R
PROVIDER: S-EPMC7828521 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Publications
Favipiravir in Therapy of Viral Infections.
Łagocka Ryta R Dziedziejko Violetta V Kłos Patrycja P Pawlik Andrzej A
Journal of clinical medicine 20210113 2
Favipiravir (FPV) is a novel antiviral drug acting as a competitive inhibitor of RNA-dependent RNA polymerase (RdRp), preventing viral transcription and replication. FPV was approved in Japan in 2014 for therapy of influenza unresponsive to standard antiviral therapies. FPV was also used in the therapy of Ebola virus disease (EVD) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this review, we discuss the mechanisms of action, pharmacokinetic parameters, toxicity, ...[more]
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