Unknown

Dataset Information

0

Replicative capacity of four porcine enteric coronaviruses in LLC-PK1 cells.


ABSTRACT: Enteric coronaviruses (CoVs) are major pathogens that cause diarrhea in piglets. To date, four porcine enteric CoVs have been identified: transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and HKU2-like porcine enteric alphacoronavirus (PEAV). In this study, we investigated the replicative capacity of these four enteric CoVs in LLC-PK1 cells, a porcine kidney cell line. The results showed that LLC-PK1 cells are susceptible to all four enteric CoVs, particularly to TGEV and PDCoV infections, indicating that LLC-PK1 cells can be applied to porcine enteric CoV research in vitro, particularly for coinfection studies.

SUBMITTER: Xiao W 

PROVIDER: S-EPMC7831621 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

Replicative capacity of four porcine enteric coronaviruses in LLC-PK1 cells.

Xiao Wenwen W   Wang Xunlei X   Wang Jing J   Fang Puxian P   Xiao Shaobo S   Fang Liurong L  

Archives of virology 20210125 3


Enteric coronaviruses (CoVs) are major pathogens that cause diarrhea in piglets. To date, four porcine enteric CoVs have been identified: transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and HKU2-like porcine enteric alphacoronavirus (PEAV). In this study, we investigated the replicative capacity of these four enteric CoVs in LLC-PK1 cells, a porcine kidney cell line. The results showed that LLC-PK1 cells are susceptible to all  ...[more]

Similar Datasets

| S-EPMC3293519 | biostudies-literature
| S-EPMC2695801 | biostudies-literature
| S-EPMC9577394 | biostudies-literature
| S-EPMC7194928 | biostudies-literature
| S-EPMC8266444 | biostudies-literature
2020-03-01 | GSE110832 | GEO
| S-EPMC7117161 | biostudies-literature
| S-EPMC1161713 | biostudies-other
| S-EPMC9032155 | biostudies-literature
| S-EPMC6732448 | biostudies-literature