Ontology highlight
ABSTRACT:
SUBMITTER: Binieda K
PROVIDER: S-EPMC7831947 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Binięda Katarzyna K Rzepnikowska Weronika W Kolakowski Damian D Kaminska Joanna J Szczepankiewicz Andrzej Antoni AA Nieznańska Hanna H Kochański Andrzej A Kabzińska Dagmara D
International journal of molecular sciences 20210118 2
Charcot-Marie-Tooth disease (CMT) is a heritable neurodegenerative disease that displays great genetic heterogeneity. The genes and mutations that underlie this heterogeneity have been extensively characterized by molecular genetics. However, the molecular pathogenesis of the vast majority of CMT subtypes remains terra incognita. Any attempts to perform experimental therapy for CMT disease are limited by a lack of understanding of the pathogenesis at a molecular level. In this study, we aim to i ...[more]