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Automated medical diagnosis of COVID-19 through EfficientNet convolutional neural network.

ABSTRACT: COVID-19 infection was reported in December 2019 at Wuhan, China. This virus critically affects several countries such as the USA, Brazil, India and Italy. Numerous research units are working at their higher level of effort to develop novel methods to prevent and control this pandemic scenario. The main objective of this paper is to propose a medical decision support system using the implementation of a convolutional neural network (CNN). This CNN has been developed using EfficientNet architecture. To the best of the authors' knowledge, there is no similar study that proposes an automated method for COVID-19 diagnosis using EfficientNet. Therefore, the main contribution is to present the results of a CNN developed using EfficientNet and 10-fold stratified cross-validation. This paper presents two main experiments. First, the binary classification results using images from COVID-19 patients and normal patients are shown. Second, the multi-class results using images from COVID-19, pneumonia and normal patients are discussed. The results show average accuracy values for binary and multi-class of 99.62% and 96.70%, respectively. On the one hand, the proposed CNN model using EfficientNet presents an average recall value of 99.63% and 96.69% concerning binary and multi-class, respectively. On the other hand, 99.64% is the average precision value reported by binary classification, and 97.54% is presented in multi-class. Finally, the average F1-score for multi-class is 97.11%, and 99.62% is presented for binary classification. In conclusion, the proposed architecture can provide an automated medical diagnostics system to support healthcare specialists for enhanced decision making during this pandemic scenario.

SUBMITTER: Marques G

PROVIDER: S-EPMC7836808 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Project description:BackgroundAutomatic segmentation and localization of lesions in mammogram (MG) images are challenging even with employing advanced methods such as deep learning (DL) methods. We developed a new model based on the architecture of the semantic segmentation U-Net model to precisely segment mass lesions in MG images. The proposed end-to-end convolutional neural network (CNN) based model extracts contextual information by combining low-level and high-level features. We trained the proposed model using huge publicly available databases, (CBIS-DDSM, BCDR-01, and INbreast), and a private database from the University of Connecticut Health Center (UCHC).ResultsWe compared the performance of the proposed model with those of the state-of-the-art DL models including the fully convolutional network (FCN), SegNet, Dilated-Net, original U-Net, and Faster R-CNN models and the conventional region growing (RG) method. The proposed Vanilla U-Net model outperforms the Faster R-CNN model significantly in terms of the runtime and the Intersection over Union metric (IOU). Training with digitized film-based and fully digitized MG images, the proposed Vanilla U-Net model achieves a mean test accuracy of 92.6%. The proposed model achieves a mean Dice coefficient index (DI) of 0.951 and a mean IOU of 0.909 that show how close the output segments are to the corresponding lesions in the ground truth maps. Data augmentation has been very effective in our experiments resulting in an increase in the mean DI and the mean IOU from 0.922 to 0.951 and 0.856 to 0.909, respectively.ConclusionsThe proposed Vanilla U-Net based model can be used for precise segmentation of masses in MG images. This is because the segmentation process incorporates more multi-scale spatial context, and captures more local and global context to predict a precise pixel-wise segmentation map of an input full MG image. These detected maps can help radiologists in differentiating benign and malignant lesions depend on the lesion shapes. We show that using transfer learning, introducing augmentation, and modifying the architecture of the original model results in better performance in terms of the mean accuracy, the mean DI, and the mean IOU in detecting mass lesion compared to the other DL and the conventional models.

Project description:Background and objectiveSARS-CoV-2, a novel strain of coronavirus' also called coronavirus disease 19 (COVID-19), a highly contagious pathogenic respiratory viral infection emerged in December 2019 in Wuhan, a city in China's Hubei province without an obvious cause. Very rapidly it spread across the globe (over 200 countries and territories) and finally on 11 March 2020 World Health Organisation characterized it as a "pandemic". Although it has low mortality of around 3% as of 18 May 2021 it has already infected 164,316,270 humans with 3,406,027 unfortunate deaths. Undoubtedly the world was rocked by the COVID-19 pandemic, but researchers rose to all manner of challenges to tackle this pandemic by adopting the shreds of evidence of ML and AI in previous epidemics to develop novel models, methods, and strategies. We aim to provide a deeper insight into the convolutional neural network which is the most notable and extensively adopted technique on radiographic visual imagery to help expert medical practitioners and researchers to design and finetune their state-of-the-art models for their applicability in the arena of COVID-19.MethodIn this study, a deep convolutional neural network, its layers, activation and loss functions, regularization techniques, tools, methods, variants, and recent developments were explored to find its applications for COVID-19 prognosis. The pipeline of a general architecture for COVID-19 prognosis has also been proposed.ResultThis paper highlights recent studies of deep CNN and its applications for better prognosis, detection, classification, and screening of COVID-19 to help researchers and expert medical community in multiple directions. It also addresses a few challenges, limitations, and outlooks while using such methods for COVID-19 prognosis.ConclusionThe recent and ongoing developments in AI, MI, and deep learning (Deep CNN) has shown promising results and significantly improved performance metrics for screening, prediction, detection, classification, forecasting, medication, treatment, contact tracing, etc. to curtail the manual intervention in medical practice. However, the research community of medical experts is yet to recognize and label the benchmark of the deep learning framework for effective detection of COVID-19 positive cases from radiology imagery.

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Automated medical diagnosis of COVID-19 through EfficientNet convolutional neural network.

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